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PhAST: The fastest Phenotypic Antibiotic Susceptibility Test

PhAST

DIAGNOSTIC INFORMATION RIGHT WHEN YOU NEED IT

We believe that innovative technology can transform the way we fight infectious diseases. PhAST is developing rapid diagnostic technology to provide actionable information on pathogens, with the ultimate goal of making the world a healthier place.

PhAST brings the power of single-cell imaging to microbiology, harnessing the immediate and extensive information that imaging reveals about microorganisms. Our multidisciplinary team is passionate about revolutionizing a broad range of diagnostic testing approaches through single-cell imaging, to massively accelerate the detection, identification and antibiotic susceptibility testing of pathogens – from days down to minutes. Imagine imaging at the scale of microbes!

News

Award from the Longitude Prize Committee

On November 21, 2016, PhAST was awarded the Discovery Award from the Longitude Prize Committee . PhAST is excited to compete in the Longitude 10 million pound Prize for a diagnostic test that contributes to solve the global problem of antibiotic resistance.

Award

PhAST is now official

On March 6, 2017, PhAST has become official! PhAST Corp. is now a Delaware Corporation and certified to do business in the US.

THE TEAM

Our team includes world-leading experts in single-cell microbial imaging and microfluidic systems.

Kwangmin Son

Kwangmin Son, PhD

CEO & Co-founder

Kwangmin is co-founder and CEO of PhAST. Kwangmin trained as an engineer working at the interface of mechanical and biological engineering at MIT, where he earned his PhD (2015) and worked as a post-doctoral researcher. Kwangmin brings strong expertise in combining microbial imaging and microfluidics, having worked on some of the most challenging bacterial and viral imaging problems to date. He hopes that PhAST’s diagnostic technology will significantly help reduce the mis-usage and over-usage of antibiotics, thus contributing to fight the spread of antibiotic resistance.




Roman Stocker

Roman Stocker, PhD

Co-founder

Roman is co-founder of PhAST. Roman is a professor of engineering at MIT (2005-present) and ETH Zurich (2015-present). Roman pioneered the field of environmental microfluidics, a single-cell imaging based approach to study the response of microorganisms to chemical and physical stimuli. Roman is a world-renowned expert in microbial biophysics, has worked with a broad range of organisms to date, and brings original engineering approaches to microbiological problems. In acknowledgement of his seminal work Roman has received major awards, including an NSF CAREER award and a prestigious Investigator award from the Gordon and Betty Moore Foundation. Roman has published nearly 100 papers, including more than 20 in Nature, Science and PNAS. Roman’s vision is that new, creative engineering technology can make a substantial contribution to the global problem of antibiotic resistance.

 
 
 

SCIENTIFIC ADVISORS


Award

Prof. Andrew Onderdonk is the Director of the Clinical Microbiology Laboratory at Brigham and Women’s Hospital in Boston and a Professor of Pathology at Harvard Medical School. His research encompasses several areas related to human microbial flora and its role in health and disease, including the pathogenesis of microorganisms and the in vivo and in vitro efficacy of antimicrobials. Dr. Onderdonk advises PhAST with information and feedback on clinical issues.


Award

Prof. Marvin Whiteley is the Director of the LaMontagne Center for Infectious Disease at The University of Texas, Austin. Dr. Whiteley’s research focuses on antibiotic resistance and the development of therapeutics to treat polymicrobial infections. He has received numerous national and international awards and is currently a Burroughs Welcome Pathogenesis of Infectious Disease Investigator, a member of the American Academy of Microbiology, and a Kavli Institute Fellow of the National Academy of Sciences.

Join the PhAST Team!

We have 3 Openings.

Come do the best work of your life at PhAST and help revolutionize microbiology through the power of single-cell imaging, in a highly motivated, energetic and interdisciplinary team! Positions are available immediately. If interested, please email your CV and a cover letter to careers@phastdiagnostics.com.

Location: Boston/Cambridge, Massachusetts, United States

Job Description

We are seeking an experienced research scientist with expertise in antibiotics to join PhAST’s founding team. The successful candidate will play a leading role in developing innovative pathogen ID/AST technology, with salary and equity entitlement options based on commitment and experience. The candidate must be passionate about developing new in vitro diagnostic platforms in an early-stage startup and building the Microbiology Team at PhAST. Initial responsibilities at our two performance sites will include:

R&D site (Kendall Square, Cambridge)

  • Advancing PhAST’s technology platform by optimizing assay protocols to enhance diagnostic accuracy, for different clinically relevant conditions.
  • Expanding PhAST’s core database by performing experiments on reference organisms from the ATCC and the FDA-CDC Antimicrobial Resistance Isolate Bank.
  • Contributing microbiology expertise to the development of automated diagnostic decision-making algorithms.

Clinical testing site (Charles/MGH, Boston)

  • Performing initial clinical testing of PhAST’s technology using fresh human isolate samples in collaboration with a leading clinical microbiology laboratory.
  • Validating PhAST’s technology through comparison with gold standard methods.
  • Advancing PhAST’s technology by devising and integrating additional screening and diagnostic tools.

Desired Experience and Qualifications

  • PhD in microbiology or molecular biology with focus on antibiotics.
  • Strong understanding of antibiotic resistance mechanisms and of antibiotic effects on phenotypic changes and microbial growth.
  • Extensive wet-lab skills (experience working with clinically relevant human pathogens a plus; microscopy experience a plus).

Location: Boston/Cambridge, Massachusetts, United States

Job Description

We are seeking a talented and creative research scientist with expertise in microbiology to join PhAST’s team. The successful candidate must be passionate about playing a leading role in developing innovative pathogen identification and screening technology in an early-stage startup. Salary and equity entitlement options will be based on commitment and experience. Initial responsibilities will include:

  • Testing and optimizing PhAST’s technology for a range of user cases.
  • Working in tight collaboration with engineers to advance PhAST’s technology by devising and integrating additional screening and diagnostic elements.
  • Validating PhAST’s technology through comparison with gold standard methods.
  • Contributing microbiology expertise to the development of automated diagnostic decision-making algorithms.

Desired Experience and Qualifications

  • PhD in microbiology or molecular biology with a demonstrated track record of excellence.
  • Extensive wet-lab skills (experience with pathogens a plus; microscopy experience a plus).
  • Creativity in troubleshooting microbial assays and overcoming technical hurdles, and a keen desire to innovate.
  • Excellent written and verbal communication skills with a track record of authorship in scientific publications or grants.
  • Desire to work in a fast-paced and highly collaborative environment with a worldclass team.
  • Legally eligible to work in the United States.

Location: Boston/Cambridge, Massachusetts, United States

Job Description

We are seeking a talented and driven research associate with expertise in microbiology to join PhAST’s team. The successful candidate must be passionate about testing and developing innovative pathogen identification and screening technology in an early-stage startup. Salary and equity entitlement options will be based on commitment and experience. Initial responsibilities will include:

  • Testing PhAST’s technology for a range of user cases.
  • Validating PhAST’s technology through comparison with gold standard methods.
  • Working with senior research scientists and engineers to advance PhAST’s technology.

Desired Experience and Qualifications

  • B.Sc. in microbiology/molecular biology or B.Eng. in Bioengineering with a demonstrated track record of excellence
  • Demonstrated wet-lab skills (experience with pathogens a plus; microscopy experience a plus).
  • A rigorous and systematic approach to data acquisition and analysis.
  • A desire to overcome technical hurdles through creativity and dedication.
  • Excellent written and verbal communication skills.
  • Desire to work in a fast-paced and highly collaborative environment with a world-class team.
  • Legally eligible to work in the United States.

CONTACT INFORMATION

Lets get in touch. Send us a message!

Email: info@phastdiagnostics.com